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Children are routinely recommended to receive the first dose at age 12 through 15 months and the second dose at age 4 through 6 years old. ACIP vaccine recommendations and the contraindications and precautions.
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Breakthrough infection can occur after 1 or 2 doses of vaccine.
. Breakthrough varicella is defined as varicella due to infection with wild-type VZV occurring more than 42 days after varicella vaccination. With decreasing incidence of varicella overall and increasing varicella vaccination coverage more than half of varicella cases reported during the mature phase of the. Post-herpetic neuralgia PHN which can be debilitating is the most frequent.
HZ is characterized by neuropathic pain and dermatomal vesicular rash. CDC recommends 2 doses of varicella chickenpox vaccine for children adolescents and adults to protect against varicella. Herpes zoster HZ occurs most frequently among older adults and immunocompromised persons.
Primary varicella-zoster virus infection causes varicella chickenpox and reactivated infection results in herpes zoster shingles.
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